**Objective:** The study aimed to explore the experiences of designers and patients (or their carers) cocreating in an academic hospital–based makerspace, using a bottom-up approach.
**Methods:** A generic qualitative study was conducted using semi structured individual interviews based on the Sunnybrook team–based competencies and design thinking methodology. A heterogeneous sample of 12 participants was recruited from a makerspace in an academic hospital in the Netherlands, comprising 6 with a designer’s perspective and 6 with a patient’s perspective. Most participants were involved in collaborative pairs, representing both perspectives within the same innovation project. Data were analyzed thematically.
**Results:** Four key themes emerged from the data: (1) dealing with the patient’s situations, (2) integrating different perspectives, (3) feeling valuable and useful, and (4) dynamic interplay and engagement. Collaboration with patients in this hospital-based makerspace was perceived as valuable for innovation development, benefiting from diverse perspectives. However, the degree of patient involvement varied, influenced by factors such as the patient’s health status, reachability, and interest in innovation development.
**Conclusions:** This study highlights the complexity of developing technical innovations that involve hospitalized patients. It offers valuable insights into how both patients and designers generally viewed their collaboration in the makerspace positively. Practical recommendations for hospital-based makerspaces include respecting patient autonomy, involving patients early and consistently throughout all development phases, maintaining communication beyond the formal collaboration period, and actively seeking feedback.
