IL-6, calcium, salivary amylase activity and cortisol as a salivary biomarker-combination associated with obesity: a pilot study

Authors H. Al Habobe, E. B. Haverkort, K. Nazmi, L. K. Van Nieukerken, V. E. A. Gerdes, F. J. Bikker, R. H. H. Pieters
Published in Frontiers in Dental Medicine
Publication date 2026
Research groups Innovative Testing in Life Sciences and Chemistry, Innovations in Preventive Care
Type Article

Summary

Introduction: As obesity continues to escalate to pandemic levels worldwide, innovative approaches for early diagnosis, risk stratification, and disease monitoring are urgently needed. Saliva presents a promising non-invasive method for biomarker-based screening in obesity. Objective: This study aimed to utilize a multi-biomarker approach to explore associations between salivary biomarkers and obesity. This was done by measuring a pre-selected panel of obesity-related salivary biomarkers and comparing their levels between individuals with and without obesity.

Downloads en links

On this publication contributed

  • Liesbeth Haverkort | Researcher | Research group Innovations in Preventive Care
    E. B. Haverkort
    • Researcher
    • Research group: Innovations in Preventive Care
  • Raymond Pieters | Professor | Research group Innovative Testing in Life Sciences & Chemistry
    R. H. H. Pieters
    • Professor
    • Research group: Innovative Testing in Life Sciences and Chemistry
Language English
Published in Frontiers in Dental Medicine
Key words calcium, cortisol, IL-6, obesity, sAA, saliva
Digital Object Identifier 10.3389/fdmed.2025.1725865
Page range 1-8

Innovative Testing in Life Sciences and Chemistry