Research group Innovative Testing in Life Sciences & Chemistry
The Research group Innovative Testing in Life Sciences & Chemistry develops and applies methods to determine the effects of substances present in our environment, food and medicines, without the use of animal testing.
Lines of research within the research group
Virtual Human Platform 4 Safety Assessment
Imagine a world in which we perform precision safety testing of chemicals and pharmaceuticals without using laboratory animals. Imagine that this safety can be assessed for vulnerable groups.
ONTOX: predicting toxicity with artificial intelligence
ONTOX aims to deliver a generic strategy for using artificial intelligence (AI) that can be applied to predict toxicity in humans of any chemical at any dose. With the use of big data, novel predictive algorithms will be used to effectively indicate whether a compound of interest provides a risk for human health.
The value of vital tissue
In this project we will inform and involve the general public about biomedical research: in particular the (in)possibilities of the use of human tissue.
Publications
- Natural language processing in toxicology: Delineating adverse outcome pathways and guiding the application of new approach methodologies
- Kinetics of Physiological Responses as a Measure of Intensity and Hydration Status During Experimental Physical Stress in Human Volunteers
- Plasma citrulline concentration, a marker for intestinal functionality, reflects exercise intensity in healthy young men
Education
In our research we strive to apply advanced analytical chemical and biological techniques to enable innovations in the health and nutrition domain. We investigate both beneficial and potentially harmful effects of natural substances, particularly on the intestines and the immune system. Collaborations with our partners (start-ups and established companies, other knowledge institutes) are focused on themes such as food safety, protein transition, and the development of innovative production methods for medicines.
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Collaboration
The research group formed the basis of the Innovation Lab (iLab) Life Sciences & Chemistry in Utrecht, which provides the space for collaboration with professionals who are active in professional practice. We also work closely with other research institutes, as well as with partners from the (international) business community.
