Virtual Human Platform 4 Safety Assessment
Imagine a world in which we perform precision safety testing of chemicals and pharmaceuticals without using laboratory animals. Imagine that this safety can be assessed for vulnerable groups. Imagine that we know how these substances interact with human biology and physiology and how they can be used safely at home, school or at work.
Objective
Assessing the safety of chemicals and pharmaceuticals without using laboratory animals. This is our vision for the future, the vision that underlies the development of the Virtual Human Platform for safety assessment, VHP4Safety.
Results
The Virtual Human Platform will be developed within three interacting research lines (RL):
- RL1: building the platform
- RL2: feeding the platform with newly generated data
- RL3: implementing the platform to ensure stakeholders’ acceptance, governance and sustainability
Duration
01 June 2021 - 31 May 2026
Approach
The VHP integrates data on human physiology, chemical characteristics and perturbations of biological pathways in an inclusive and integrated manner that incorporates:
- human-relevant scenarios to discriminate vulnerable groups
- chemicals from different sectors
- different regulatory and stakeholder needs
HU researchers involved in the research
Collaboration with knowledge partners
VHP4Safety – the Virtual Human Platform for safety assessment project NWA 1292.19.272 is part of the NWA research program ‘Research along Routes by Consortia (ORC)’, which is funded by the Netherlands Organization for Scientific Research (NWO). With a budget of over 10 million Euros, the project starts on June 1, 2021 and will last for the duration of 5 years.
