The Noncaloric Sweetener Rebaudioside A Stimulates Glucagon-Like Peptide 1 Release and Increases Enteroendocrine Cell Numbers in 2-Dimensional Mouse Organoids Derived from Different Locations of the Intestine
Authors | Raymond Pieters, Susanne Muckenschnab, Jocelijn Meijerink, Renger F Witkamp, Henk FJ Hendriks, Jean Paul ten Klooster, Nikkie van der Wielen |
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Published in | The Journal of Nutrition |
Publication date | 26 October 2016 |
Research groups | Innovative Testing in Life Sciences and Chemistry |
Type | Article |
Summary
Abstract from the journal: Glucagon-like peptide 1 (GLP-1) contributes to satiety and plays a pivotal role in insulin secretion and glucose homeostasis. Similar to GLP-1, peptide YY (PYY) and cholecystokinin also influence food intake. The secretion of these hormones by enteroendocrine cells along the intestine is modulated by nutrients. Preparations from the Stevia rebaudiana plant, including rebaudioside A, are increasingly being used as noncaloric sweeteners. doi: 10.3945/jn.116.232678
On this publication contributed
Language | English |
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Published in | The Journal of Nutrition |
Year and volume | 146 11 |
ISBN/ISSN | URN:ISSN:0022-3166 |
Key words | glucagon-like peptide 1, GLP-1, peptide YY, gut hormone, ileum, jejunum, duodenum |