The focus of this chapter is on learning for and in practice and learning environments that afford such learning. In a systematic review of literature on learning processes and learning activities of (future) professionals we searched for designable elements of learning environments which may elicit learning. We start from a socio-cultural perspective on learning. 30 studies were included, in which three specific foci of learning were recognized, namely (a) learning how to act in vocational practice, (b) developing vocational knowledge, and (c), developing a vocational identity. Results showed several designable elements of learning environments that seem promising in supporting learning.